BDBM50652783 CHEMBL5649162

SMILES C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(-c5[nH]c(=O)c(CC(C)C)nc5-c5ccccc5)cc4)CC3)c2c1

InChI Key InChIKey=CNDUFZZEFPZYCZ-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50652783   

TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652783(CHEMBL5649162)
Affinity DataIC50: 1.14E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652783(CHEMBL5649162)
Affinity DataIC50: 119nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652783(CHEMBL5649162)
Affinity DataIC50: 1.63E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652783(CHEMBL5649162)
Affinity DataKi:  57nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652783(CHEMBL5649162)
Affinity DataKi:  1.43E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed