BDBM50651393 CHEMBL5632306

SMILES COc1cccc(-c2ccc3ncnc(Nc4ccc5scnc5c4)c3c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50651393   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50651393(CHEMBL5632306)
Affinity DataIC50: 49nMAssay Description:Inhibition of N-terminal polyHis-tagged human RIPK2 (8 to 310 residues) expressed in Sf9 cells using MBP as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50651393(CHEMBL5632306)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal polyHis-tagged human RIPK1 (1 to 321 residues) expressed in Sf9 cells using MBP as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 4(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50651393(CHEMBL5632306)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal polyHis-tagged human RIPK4 (1 to 321 residues) expressed in Sf9 cells using MBP as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed