BDBM50651192 CHEMBL5633837

SMILES COc1cc(-c2n[nH]c3ncc(-c4ccc(C)c(NCCO)c4)cc23)cc(OC)c1OC

InChI Key InChIKey=OATHVDKMFZZHHN-UHFFFAOYSA-N

Data  2 IC50  11 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50651192   

TargetTyrosine-protein kinase ABL1(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyotonin-protein kinase(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  26nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  36nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  2.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  6.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 16(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataKd:  11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataIC50: 88nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Southern University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651192(CHEMBL5633837)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed