BDBM50649698 CHEMBL5619652

SMILES Cc1ccc(C(=O)Nc2cc(CN3CCN(C)CC3)cc(C(F)(F)F)c2)cc1C#Cc1cnc2ccc(N3CCOCC3)nn12

InChI Key InChIKey=IWRYPZJFNFQTHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649698   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50649698(CHEMBL5619652)
Affinity DataIC50: 41nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50649698(CHEMBL5619652)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed