BDBM50646098 CHEMBL5589636

SMILES CNC(=O)c1cnc(S(C)(=O)=O)nc1N1CCC[C@H](n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1

InChI Key InChIKey=HKIXPZAHPHKWJJ-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50646098   

TargetTyrosine-protein kinase BTK(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50646098(CHEMBL5589636)
Affinity DataKi:  5.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed