BDBM50645749 CHEMBL5083143

SMILES c1ccc2c(-c3coc4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc2c1

InChI Key InChIKey=FFLJVBPCONQSQW-UHFFFAOYSA-N

Data  9 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50645749   

TargetSerine/threonine-protein kinase receptor R3(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50:  225nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50:  1.07E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50:  2.86E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50: >2.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50:  997nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50:  497nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataEC50:  27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 539nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 751nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 501nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 41nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 3.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 3.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Affinity DataIC50: 425nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645749(CHEMBL5083143)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed