BDBM50645537 CHEMBL5594704

SMILES CC(=O)c1c[nH]c(-c2sc(N(c3cnn(-c4ccncc4F)c3)C3CC3)nc2C(N)=O)c1

InChI Key InChIKey=QCEHAYINFMPPPM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50645537   

TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 74nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 183nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 3.69E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-2B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 6.34E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed