BDBM50645536 CHEMBL5591770

SMILES COc1cnccc1-n1cc(N(c2nc(C(N)=O)c(-c3cc(C(C)=O)c[nH]3)s2)C2CC2)cn1

InChI Key InChIKey=FHTCHCUICJOIGJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50645536   

TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 56nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 82nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-2B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed