BDBM50645374 CHEMBL5574295

SMILES Cc1ccc2c(-c3ccc4ncnc(N[C@H](CO)c5ccccc5)c4c3)c[nH]c2n1

InChI Key InChIKey=MNVPCONHWCXDES-UHFFFAOYSA-N

Data  10 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50645374   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 0.680nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 1.42E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 401nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK3(Homo sapiens)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataEC50:  11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645374(CHEMBL5574295)
Affinity DataEC50:  17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed