BDBM50644179 CHEMBL5573027

SMILES Cc1cc(NC(=O)C(=O)N2C[C@@H](C)CC[C@@H]2c2ccc3scnc3c2)cnc1N

InChI Key InChIKey=NXXBDYHMHHINFC-UHFFFAOYSA-N

Data  3 KI  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50644179   

TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644179(CHEMBL5573027)
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644179(CHEMBL5573027)
Affinity DataKd:  1.90nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644179(CHEMBL5573027)
Affinity DataIC50: 262nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644179(CHEMBL5573027)
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644179(CHEMBL5573027)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644179(CHEMBL5573027)
Affinity DataKi:  9.30nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed