BDBM50642871 CHEMBL5591019

SMILES C[C@@H](Nc1c[nH]c(=O)c(C(=O)Nc2ccc(CN3CCN(C)CC3)cc2)c1)c1c(Cl)ccc(F)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50642871   

TargetHigh affinity nerve growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642871BDBM50642871(CHEMBL5591019)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642871BDBM50642871(CHEMBL5591019)
Affinity DataIC50: 20nMAssay Description:Inhibition of TRKA (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Shanghai Tech University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642871BDBM50642871(CHEMBL5591019)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human TrkB by Eurofins kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Shanghai Tech University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642871BDBM50642871(CHEMBL5591019)
Affinity DataIC50: 5.53E+3nMAssay Description:Inhibition of human TrkC by Eurofins kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed