BDBM50642856 CHEMBL5568675

SMILES CC#C[C@H](C)n1cc(C(F)(F)F)cc(-c2cccc([C@]3(c4nncn4C)C[C@@H](C)C3)c2)c1=O

InChI Key InChIKey=XXDSWZGTJRNCFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642856   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642856(CHEMBL5568675)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL(Homo sapiens)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642856(CHEMBL5568675)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed