BDBM50642844 CHEMBL5542469

SMILES Cn1cnnc1[C@@H](c1cccc(-c2cc(C(F)(F)F)c[nH]c2=O)c1)C1CCC1

InChI Key InChIKey=RZWDFGBPPKSYAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642844   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642844(CHEMBL5542469)
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL(Homo sapiens)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642844(CHEMBL5542469)
Affinity DataIC50: 410nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed