BDBM50642827 CHEMBL5584155

SMILES CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccncc1)NC(=O)CNC(=O)CC[C@H](NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1)C(=O)O)C(=O)Nc1ccc(C(=O)N2CCC(C(=O)N[C@H](CCCCN)C(=O)N3CC[C@H](N)C3)CC2)cc1

InChI Key InChIKey=YQYRZEZDMHAWCC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50642827   

TargetMatrilysin(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStromelysin-1(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 730nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50642827(CHEMBL5584155)
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed