BDBM50642392 CHEMBL5571636

SMILES C[C@@H](C(=O)N1CCN(c2ncc(C(F)(F)F)cn2)CC1)n1cc2cccc(C(N)=O)c2n1

InChI Key InChIKey=ZXYKQNYSXHNQMV-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50642392   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 4.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 303nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 901nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 694nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 377nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP12(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 664nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642392(CHEMBL5571636)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed