BDBM50641972 CHEMBL5565621

SMILES COc1ccc2c(c1CC(=O)O)Oc1c(ccc(OC)c1CC(=O)N1[C@H](c3cc([N+](=O)[O-])cc(OC)c3OCC(=O)O)N(C)C(=O)[C@@H]1C)C2(C)C

InChI Key InChIKey=PGHDTEOXCASCRK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50641972   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50641972(CHEMBL5565621)
Affinity DataIC50: 340nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase CBL-B(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50641972(CHEMBL5565621)
Affinity DataKd:  280nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)