BDBM50641496 CHEMBL5568622

SMILES C[C@](O)(CN1CC2CC(C1)N2c1ccc(C#N)cc1)C(=O)Nc1cnc(C#N)c(C(F)(F)F)c1

InChI Key InChIKey=OUFWUTDTAQRRHQ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50641496   

TargetProtein cereblon/CUL4A/AR(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50641496(CHEMBL5568622)
Affinity DataIC50: 135nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEstrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50641496(CHEMBL5568622)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProgesterone receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50641496(CHEMBL5568622)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50641496(CHEMBL5568622)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein cereblon/CUL4A/AR(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50641496(CHEMBL5568622)
Affinity DataKi:  780nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed