BDBM50638607 CHEMBL5563355

SMILES Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(-c4nc5c(C(N)=O)cccc5[nH]4)cc3)cc3c2cnn3C(C)C)c(=O)[nH]1

InChI Key InChIKey=QCDZWDMYQRCVLA-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50638607   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638607(CHEMBL5563355)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638607(CHEMBL5563355)
Affinity DataKd:  4.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638607(CHEMBL5563355)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed