BDBM50637886 Culmerciclib

SMILES CC(C)c1c2cc(-c3nc(Nc4ccc(N5CCNCC5)cn4)ncc3F)ccc2nn1C

InChI Key InChIKey=LLFOBMRPWNABCB-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50637886   

TargetCyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 0.350nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 0.490nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 556nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 2.09E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 246nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50637886(Culmerciclib)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed