BDBM50636824 CHEMBL5542205

SMILES C=CC(=O)N1CC[C@H](n2cc(-c3ccncc3)c(-c3cccc(/C=C/c4ncc(C5CC5)o4)c3)n2)C1

InChI Key InChIKey=SVLLKLFGGWAXTK-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50636824   

TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Affinity DataIC50: 340nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Affinity DataIC50: 89nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Affinity DataIC50: 85nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50636824(CHEMBL5542205)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed