BDBM50636431 CHEMBL5561973

SMILES FC(F)c1c(Br)c(Br)cc2c1nc(N1CCNCC1)n2C1CCOCC1

InChI Key InChIKey=YRFOQHHFWYWAST-UHFFFAOYSA-N

Data  23 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50636431   

TargetDual specificity protein kinase CLK1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
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TargetMitogen-activated protein kinase 15(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 60nMMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetSerine/threonine-protein kinase TAO1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 6.68E+3nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetSerine/threonine-protein kinase haspin(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 14nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetRho-associated protein kinase 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 353nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 158nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetHomeodomain-interacting protein kinase 3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 503nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetCasein kinase I isoform alpha(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 132nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetCasein kinase II subunit alpha'(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 65nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetSerine/threonine-protein kinase pim-2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 124nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetDual specificity protein kinase CLK4(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetDual specificity protein kinase CLK2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 14nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetCyclin-C(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetCyclin-dependent kinase 19(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 25nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetCyclin-dependent kinase 8(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 7.5nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetCyclin-C(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 7.5nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 194nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 87nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 31nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 43nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 197nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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TargetCyclin-dependent kinase 19(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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TargetCyclin-dependent kinase 8(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL

LigandBDBM50636431(CHEMBL5561973)Copy SMILESCopy InChI

Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOIPubMed
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