BDBM50635605 CHEMBL5505865

SMILES CC(=O)Nc1cccc(-c2c(-c3cnn(C)c3)oc3ncnc(Oc4ccc(NC(=O)c5cccn(-c6ccc(F)cc6)c5=O)cc4)c23)c1

InChI Key InChIKey=TWBJKVMWEQKJFY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50635605   

TargetTyrosine-protein kinase Mer(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635605BDBM50635605(CHEMBL5505865)
Affinity DataIC50: 1nMAssay Description:Inhibition of MER (unknown origin) expressed in mouse BaF3 cells co-expressing TMEM assessed as inhibition of MER-driven cell proliferation incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635605BDBM50635605(CHEMBL5505865)
Affinity DataIC50: 12nMAssay Description:Inhibition of MER (unknown origin) preincubated for 15 mins followed by substrate and ATP addition and measured after 3 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635605BDBM50635605(CHEMBL5505865)
Affinity DataIC50: 12nMAssay Description:Inhibition of MerTK (unknown origin) incubated for 3 hrs in presence of substrate/ATP by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635605BDBM50635605(CHEMBL5505865)
Affinity DataIC50: 53nMAssay Description:Inhibition of Tyro3 (unknown origin) incubated for 3 hrs in presence of substrate/ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635605BDBM50635605(CHEMBL5505865)
Affinity DataIC50: 80nMAssay Description:Inhibition of AXL (unknown origin) preincubated for 15 mins followed by substrate and ATP addition and measured after 3 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed