BDBM50634630 NLRP3 Compound 4

SMILES [2H]C([2H])([2H])C(O)(c4coc(S(=O)(=O)NC(=O)Nc3c1CCCc1cc2CCCc23)c4)C([2H])([2H])[2H]

InChI Key InChIKey=HUUSXLKCTQDPGL-WFGJKAKNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634630   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50634630(NLRP3 Compound 4)
Affinity DataIC50: 5nMAssay Description:Inhibition of NLRP3 in human monocyte derived macrophages assessed as reduction in LPS-induced IL-1beta production incubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed