BDBM50634564 CHEMBL205371

SMILES O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccccc1CN1CCOCC1

InChI Key InChIKey=NBCFKFUKUXVZQS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634564   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50634564(CHEMBL205371)
Affinity DataIC50: 210nMAssay Description:Displacement of FAM-labeled probe from recombinant biotinylated Cbl-b (unknown origin) expressed in Escherichia coli BL21(DE3) Tuner cells by TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50634564(CHEMBL205371)
Affinity DataKd:  400nMAssay Description:Binding affinity to avidin-biotinylated Cbl-b at (36 to 427 residues) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed