BDBM50634534 CHEMBL5436873

SMILES [H][C@]12C[C@]3([H])C[C@]([H])(C1)CC(CC(=O)NCC(=O)Nc1ccc(cc1)C(=O)NCCCCCCC(=O)NO)(C2)C3

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50634534   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50634534(CHEMBL5436873)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant HDAC in human MM.1S cells using Boc-Lys(Epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50634534(CHEMBL5436873)
Affinity DataIC50: 133nMAssay Description:Inhibition of C-terminal 6His tagged human recombinant full length HDAC1 (1 to 482 residues) using Z- Lys(Ac)-AMC as fluorogenic substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50634534(CHEMBL5436873)
Affinity DataIC50: 246nMAssay Description:Inhibition of C-terminal flag tagged human recombinant full length HDAC2 (1 to 488 residues) using Z- Lys(Ac)-AMC as fluorogenic substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50634534(CHEMBL5436873)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of C-terminal GST tagged human recombinant full length HDAC6 (1 to 1215 residues) using Z- Lys(Ac)-AMC as fluorogenic substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed