BDBM50634518 CHEMBL5395695

SMILES Cc1cccc(c1)-c1ccc2c(C#N)c(O)c(nc2c1)C(=O)CCC(O)=O

InChI Key InChIKey=NRJXHGKKRZJQSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634518   

TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634518(CHEMBL5395695)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634518(CHEMBL5395695)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed