BDBM50634406 CHEMBL5403203

SMILES CS(=O)(=O)Nc1ccc2nc(NC(=O)Nc3ccc(O)c(Cl)c3)sc2c1

InChI Key InChIKey=BRAZSCGXXCFTNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50634406   

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634406(CHEMBL5403203)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using ALLOP as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634406(CHEMBL5403203)
Affinity DataIC50: 520nMAssay Description:Mixed type inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634406(CHEMBL5403203)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed