BDBM50634310 CHEMBL5394686

SMILES COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OCCON1CCN(C)CC1

InChI Key InChIKey=OXIJKGCVPJOUEO-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634310   

TargetEpidermal growth factor receptor(Human)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50634310(CHEMBL5394686)
Affinity DataKd: <0.200nMAssay Description:Inhibition of wild type human EGFR assessed as dissociation constant by KINOMEScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50634310(CHEMBL5394686)
Affinity DataKd:  21nMAssay Description:Inhibition of human ERBB2 assessed as dissociation constant by KINOMEScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed