BDBM50634219 CHEMBL5399611

SMILES CC(C)Sc1cc2n(c1)c(nn(CC(=O)N[C@H]1C[C@@](C)(O)C1)c2=O)C(C)C

InChI Key InChIKey=MBIFVPCZKPWCHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634219   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50634219(CHEMBL5399611)
Affinity DataIC50: 1nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as reduction in Il-1beta production preincubated for 0.5 hrs followed by LPS treatment for 3.5 hrs a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed