BDBM50634217 CHEMBL5411212

SMILES CC(C)c1nn(CC(=O)N[C@H]2C[C@@](C)(O)C2)c(=O)c2cc3ccsc3n12

InChI Key InChIKey=MGKGWRNCYIUMHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634217   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50634217(CHEMBL5411212)
Affinity DataIC50: 18nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as reduction in Il-1beta production preincubated for 0.5 hrs followed by LPS treatment for 3.5 hrs a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed