BDBM50634211 CHEMBL5440362
SMILES CC(C)n1nc(CC(=O)Nc2ccc3n(C)c(=O)[nH]c3c2)c(=O)c2ccc(Br)cc12
InChI Key InChIKey=SWQSQWWVOIEXPK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50634211
Affinity DataIC50: 42nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as reduction in IL-1beta production preincubated for 30 mins followed by LPS addition measured after...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as reduction in TNF alpha level preincubated for 30 mins followed by LPS addition measured after 6 h...More data for this Ligand-Target Pair