BDBM50634208 CHEMBL5396495
SMILES CCNc1nc2c(nn(CC(=O)Nc3ccc4nncn4c3)c(=O)c2s1)C(C)C
InChI Key InChIKey=WMPFEPQZHBOCQE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50634208
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as reduction in IL-1beta production preincubated for 30 mins followed by LPS addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as reduction in TNF alpha level preincubated for 30 mins followed by LPS addition measured after 6 h...More data for this Ligand-Target Pair