BDBM50634200 CHEMBL5429355
SMILES CC(C)c1nn(CC(=O)N[C@@H]2CCCN(C2)C2CCC2)c(=O)c2cc3sc(Cl)cc3n12
InChI Key InChIKey=XWCHQOIWKADGEE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50634200
Affinity DataIC50: 0.300nMAssay Description:Inhibition of NLRP3 in LPS/nigericin induced PMA-differentiated human THP-1 cells assessed as reduction in IL-1beta production measured after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of NLRP3 in LPS/nigericin induced PMA-differentiated human THP-1 cells assessed as reduction in TNFalpha level measured after 3 hrsMore data for this Ligand-Target Pair