BDBM50634197 CHEMBL5419065

SMILES CN1C[C@]2(C)CCCN2[C@H](CS(=O)(=O)NC(=O)Nc2c3CCCc3cc3CCCc23)C1(C)C

InChI Key InChIKey=MKGGAGMEAQQYBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634197   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50634197(CHEMBL5419065)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in IL-1beta production preincubated for 30 mins followed by ATP addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed