BDBM50633969 CHEMBL5408556

SMILES Cn1ccc(CNc2nc(N)nc3cc(ccc23)-c2cc[nH]n2)n1

InChI Key InChIKey=CQCCWHOVLLBKPH-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633969   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50633969(CHEMBL5408556)Copy SMILESCopy InChI

Affinity DataEC50:  570nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-18 release incubated for 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50633969(CHEMBL5408556)Copy SMILESCopy InChI

Affinity DataEC50:  230nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-1beta release incubated for 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL