BDBM50633930 CHEMBL5438085

SMILES COc1ccc2nc(NC(=O)c3cc(C)n(c3C)-c3sc(C)cc3C#N)[nH]c2c1

InChI Key InChIKey=HGIMQJMGWCFYPE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50633930   

TargetATP-dependent RNA helicase DHX33(Mus musculus)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal/C-terminal 6x His-tagged wild type recombinant mouse DHX33 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProbable ATP-dependent RNA helicase DDX59(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human recombinant DDX59 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPutative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DHX32 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProbable ATP-dependent RNA helicase DDX6(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DDX6 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProbable ATP-dependent RNA helicase DHX35(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DHX35 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetATP-dependent RNA helicase DHX15(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DHX15 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProbable ATP-dependent RNA helicase DHX40(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DHX40 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNucleolar RNA helicase 2(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633930(CHEMBL5438085)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DDX21 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed