BDBM50633863 CHEMBL5426771

SMILES CN(C)C(=O)[C@@H](NC(=O)c1nnccc1-c1ccc(cc1)C(F)(F)F)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=GQZVJOGZLKPYTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633863   

TargetMHC class I polypeptide-related sequence A(Homo sapiens)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50633863(CHEMBL5426771)
Affinity DataIC50: 400nMAssay Description:Inhibition of NKG2D (unknown origin)/MICA (unknown origin) protein-protein interaction by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNKG2-D type II integral membrane protein(Homo sapiens)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50633863(CHEMBL5426771)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of NKG2D (unknown origin)/ULBP6 (unknown origin) protein-protein interaction by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed