BDBM50633761 CHEMBL5409133

SMILES Cn1cc(cn1)-c1ccc2n(nc(-c3ccc4n(C)ncc4c3)c2c1)C1CC2(CNC2)C1

InChI Key InChIKey=TZCIRZQZPQRRAY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633761   

TargetSon of sevenless homolog 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50633761(CHEMBL5409133)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at SOS1 in human HeLa cells expressing wild type KRAS assessed as increase in p-ERK level incubated for 30 mins by Western blot anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed