BDBM50633750 CHEMBL5435367

SMILES COC1=CC(=O)c2c(cc3N(C)CCc4cc5OCOc5c2c34)C1=O

InChI Key InChIKey=WDTZOTKRAGAZDC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50633750   

TargetAcetylcholinesterase(Human)
Tianjin University of Technology

Curated by ChEMBL
LigandPNGBDBM50633750(CHEMBL5435367)
Affinity DataIC50: 2.21E+5nMAssay Description:Inhibition of AChE (unknown origin) using ATCI as substrate preincubated for 15 min followed by substrate addition measured after 40 min by Ellman's ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Tianjin University of Technology

Curated by ChEMBL
LigandPNGBDBM50633750(CHEMBL5435367)
Affinity DataIC50: 8.35E+4nMAssay Description:Inhibition of BChE (unknown origin) using BTCI as substrate preincubated for 15 min followed by substrate addition measured after 40 min by Ellman's ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Tianjin University of Technology

Curated by ChEMBL
LigandPNGBDBM50633750(CHEMBL5435367)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of amyloid beta 42 (unknown origin) aggregation incubated for 24 hrs by ThT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed