BDBM50633623 CHEMBL5430524

SMILES C[C@@H](Nc1ccc(Cl)nc1C(O)=O)c1cc(C)cn2c1nc(N1CCC(F)(F)CC1)c(C#N)c2=O

InChI Key InChIKey=PXIAJBCYCFRMPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633623   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50633623(CHEMBL5430524)
Affinity DataIC50: 14nMAssay Description:Inhibition of AKT phosphorylation in human T47D cells harboring PI3Kalpha H1047R mutant incubated for 24 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed