BDBM50633617 CHEMBL5408522

SMILES C[C@@H](Nc1ccccc1C(O)=O)c1cc(C)cn2c1nc(C1CCC(F)(F)CC1)c(C#N)c2=O

InChI Key InChIKey=FSDZWQNXTKKJPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633617   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50633617(CHEMBL5408522)
Affinity DataIC50: 3nMAssay Description:Inhibition of AKT phosphorylation in human T47D cells harboring PI3Kalpha H1047R mutant incubated for 24 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50633617(CHEMBL5408522)
Affinity DataIC50: 681nMAssay Description:Inhibition of AKT phosphorylation in human SK-BR-3 cells harboring wildtype PI3Kalpha incubated for 24 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed