BDBM50633603 CHEMBL5419204

SMILES Cc1cc2c(c(c1)[C@@H](C)Nc3ccccc3C(=O)O)OC(=C(C2=O)C)N4CCC(CC4)(C)C

InChI Key InChIKey=WTFFQZJMEWAKGP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633603   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50633603(CHEMBL5419204)
Affinity DataIC50: 3nMAssay Description:Inhibition of AKT phosphorylation in human T47D cells harboring PI3Kalpha H1047R mutant incubated for 24 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50633603(CHEMBL5419204)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of AKT phosphorylation in human SK-BR-3 cells harboring wildtype PI3Kalpha incubated for 24 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed