BDBM50633518 CHEMBL5395784

SMILES Cc1nc2cc(-c3cc[nH]n3)c(NC(=O)c3cccc(n3)C(F)(F)F)cc2n1C

InChI Key InChIKey=XYHNIXWLZJJZRG-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633518   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633518(CHEMBL5395784)Copy SMILESCopy InChI

Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human IRAK4 expressed in baculovirus infected Hi-5 cells using biotinylated-Ahx-KKARFSRFAGSSPSQASFAEP...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633518(CHEMBL5395784)Copy SMILESCopy InChI

Affinity DataIC50: 5.38E+5nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FLT3 (564 to end residues) expressed in Sf21 cells using biotinylated-Ahx-GGEEEEYFELVKKKK pepti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL