BDBM50633510 CHEMBL5425128

SMILES CC(C)(O)CCn1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(O[C@H]3CCOC3)cc2n1

InChI Key InChIKey=ABUVVVLMOWRWIU-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633510   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633510(CHEMBL5425128)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human IRAK4 expressed in baculovirus infected Hi-5 cells using biotinylated-Ahx-KKARFSRFAGSSPSQASFAEP...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633510(CHEMBL5425128)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FLT3 (564 to end residues) expressed in Sf21 cells using biotinylated-Ahx-GGEEEEYFELVKKKK pepti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL