BDBM50633495 CHEMBL5434057

SMILES COc1cc(cc2cc(-c3cc4cccnc4n3C)n(N)c12)C(=O)N1CCC[C@@H](N)C1

InChI Key InChIKey=NJSZICRJHDQNCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633495   

TargetProtein-arginine deiminase type-4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50633495(CHEMBL5434057)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged PAD4 (unknown origin) expressed in Escherichia coli incubated for 1 hr by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProtein-arginine deiminase type-4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50633495(CHEMBL5434057)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged PAD4 (unknown origin) expressed in Escherichia coli BL21 (DE3) measured after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed