BDBM50633378 CHEMBL5411649

SMILES COc1cc(Cl)ccc1C(=O)Nc1cnc2[nH]cc(-c3cccnc3)c2c1

InChI Key InChIKey=DVPXOOJKYAVKSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633378   

TargetDual specificity protein kinase CLK1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50633378(CHEMBL5411649)
Affinity DataIC50: 25nMAssay Description:Inhibition of human 130-end recombinant CLK1 assessed as remaining activity using ERMRPRKRQGSVR as substrate by [gamma-32P]ATP binding based scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50633378(CHEMBL5411649)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of human full length recombinant DYRK1A assessed as remaining activity using RRRFRPASPLRGPP as substrate by [gamma-32P]ATP binding based s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed