BDBM50633366 CHEMBL5426304

SMILES Fc1cc(F)cc(CNc2cnc3[nH]cc(C4=CCCCC4)c3c2)c1

InChI Key InChIKey=CNBFWEWIGARBIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633366   

TargetDual specificity protein kinase CLK1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50633366(CHEMBL5426304)
Affinity DataIC50: 324nMAssay Description:Inhibition of human 130-end recombinant CLK1 assessed as remaining activity using ERMRPRKRQGSVR as substrate by [gamma-32P]ATP binding based scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50633366(CHEMBL5426304)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human full length recombinant DYRK1A assessed as remaining activity using RRRFRPASPLRGPP as substrate by [gamma-32P]ATP binding based s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed