BDBM50633184 CHEMBL5417485

SMILES CN1CCC[C@H]1COc1nc(N2CCN([C@@H](CC#N)C2)C(=O)C=C)c2cc(-c3cc(O)cc4ccccc34)n(C)c2n1

InChI Key InChIKey=GRICXLKEOOXBKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633184   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50633184(CHEMBL5417485)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of KRAS G12C mutant/SOS1 (unknown origin) interaction incubated for 2 hrs in presence of GTP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed