BDBM50633159 CHEMBL5423620

SMILES CNC(=O)C1Cc2nc(-c3ccc4ccccc4c3)n(c2C1)-c1ccnc(N[C@H]2CCCN(C2)C(=O)C2CC2)n1

InChI Key InChIKey=VSVFDMDYNXAZHL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50633159   

TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633159(CHEMBL5423620)
Affinity DataIC50: 0.564nMAssay Description:Inhibition of JNK3 (unknown origin) using ATF2 as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633159(CHEMBL5423620)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of JNK2 (unknown origin) incubated for 20 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633159(CHEMBL5423620)
Affinity DataIC50: 14nMAssay Description:Inhibition of JNK1 (unknown origin) incubated for 20 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633159(CHEMBL5423620)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) incubated for 20 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633159(CHEMBL5423620)
Affinity DataIC50: 752nMAssay Description:Inhibition of p38alpha (unknown origin) incubated for 20 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed