BDBM50633119 CHEMBL5438940

SMILES CCOC(=O)c1c(nc2ccc(Br)cc2c1N1CCN(CC1)c1ccccc1NS(=O)(=O)c1ccc(F)c(F)c1)-n1ccnc1

InChI Key InChIKey=PMIJPUYMIFBNCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633119   

TargetEpidermal growth factor receptor(Human)
Radhabai Kale Mahila Mahavidyalaya

Curated by ChEMBL
LigandPNGBDBM50633119(CHEMBL5438940)
Affinity DataIC50: 159nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) using poly (Glu,Tyr) as substrate incubated for 40 mins in presence of ATP by Kinase-Glo lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed